Fig 1: Effect of E. japonicum on expression of Th2-related cytokines in lung tissue. (A) Representative images of tumor necrosis factor-α (TNF-α)+ cells. (B) Representative images of interleukin-4 (IL-4)+ cells. (C) Representative images of IL-5+ cells. (D) Representative images of IL-6+ cells. (E) Representative images of IL-13+ cells. Immunopositive cells were counted in 5 randomly selected, non-overlapping fields (magnification, ×200) from 3 separately immunostained lung sections per animal. Treatment groups: panel a, control (CON); panel b, ovalbumin (OVA); panel c, dexamethasone (DEX); panel d, 60 mg/kg/day E. japonicum (E.j); panel e, 600 mg/kg/day E.j. (F) Quantitative analysis of positively-stained cells.*p<0.05 vs. CON; **p<0.001 vs. CON; $p<0.05 vs. OVA; $$p<0.001 vs. OVA; #p<0.05 vs. DEX; ##p<0.001 vs. DEX; ssp<0.001 vs. 60 mg/kg/day E.j.